1 00:00:04,550 --> 00:00:02,790 experiment work taking up the vast 2 00:00:06,309 --> 00:00:04,560 majority of the work for the astronauts 3 00:00:08,470 --> 00:00:06,319 on board the station and several new 4 00:00:10,549 --> 00:00:08,480 experiments studying bacteria were 5 00:00:12,470 --> 00:00:10,559 actually launched in return earlier this 6 00:00:14,150 --> 00:00:12,480 spring on spacex 3. 7 00:00:15,669 --> 00:00:14,160 why don't we now go find out a little 8 00:00:17,830 --> 00:00:15,679 bit more about a couple of these from 9 00:00:19,510 --> 00:00:17,840 lori meigs out at the payload operations 10 00:00:22,070 --> 00:00:19,520 integration center at the marshall space 11 00:00:23,590 --> 00:00:22,080 flight center in huntsville alabama lori 12 00:00:25,269 --> 00:00:23,600 i understand results of these 13 00:00:27,670 --> 00:00:25,279 experiments could actually help us on 14 00:00:29,269 --> 00:00:27,680 future flights to mars 15 00:00:31,349 --> 00:00:29,279 past studies have shown that bacteria 16 00:00:32,870 --> 00:00:31,359 becomes more virulent in space that's 17 00:00:35,670 --> 00:00:32,880 why we need further research to 18 00:00:37,910 --> 00:00:35,680 understand why as we travel to farther 19 00:00:39,110 --> 00:00:37,920 places out like mars the experiments 20 00:00:41,990 --> 00:00:39,120 we're talking about today are called 21 00:00:43,750 --> 00:00:42,000 brick 18. i spoke with david reed the 22 00:00:45,350 --> 00:00:43,760 lead payload engineer at the kennedy 23 00:00:47,350 --> 00:00:45,360 space center to find out more about 24 00:00:48,950 --> 00:00:47,360 these investigations and how the brick 25 00:00:51,590 --> 00:00:48,960 canisters work 26 00:00:54,310 --> 00:00:51,600 brick 18 consists of two 27 00:00:56,470 --> 00:00:54,320 investigations one investigation 28 00:00:59,270 --> 00:00:56,480 is looking at 29 00:01:01,110 --> 00:00:59,280 the effects of flying bacteria in in 30 00:01:01,990 --> 00:01:01,120 microgravity specifically looking at 31 00:01:06,870 --> 00:01:02,000 their 32 00:01:08,710 --> 00:01:06,880 antibiotics there's a lot of concern 33 00:01:10,710 --> 00:01:08,720 right now in the in the space flight 34 00:01:13,109 --> 00:01:10,720 community uh there's been other research 35 00:01:14,789 --> 00:01:13,119 done that shows that some organisms 36 00:01:17,350 --> 00:01:14,799 become more virulent 37 00:01:19,830 --> 00:01:17,360 more able to cause disease when 38 00:01:21,830 --> 00:01:19,840 they go into space and 39 00:01:23,670 --> 00:01:21,840 part of that equation is understanding 40 00:01:25,429 --> 00:01:23,680 how they might become more resistant to 41 00:01:27,270 --> 00:01:25,439 antibiotics as well which could be a 42 00:01:29,190 --> 00:01:27,280 real problem on a long-term space flight 43 00:01:31,990 --> 00:01:29,200 in some place like mars 44 00:01:35,510 --> 00:01:32,000 so this investigator has got two kind of 45 00:01:37,749 --> 00:01:35,520 common bacteria and he's applying 46 00:01:39,749 --> 00:01:37,759 antibiotics to two different antibiotics 47 00:01:41,510 --> 00:01:39,759 to them to see they each have different 48 00:01:43,429 --> 00:01:41,520 slightly different genetics in them to 49 00:01:46,710 --> 00:01:43,439 see how they respond to that treatment 50 00:01:48,950 --> 00:01:46,720 the second investigator is using a small 51 00:01:52,069 --> 00:01:48,960 plant called arabidopsis it's in the 52 00:01:54,069 --> 00:01:52,079 mustard family it's a it's a very small 53 00:01:56,310 --> 00:01:54,079 plant it only grows about this big 54 00:01:58,389 --> 00:01:56,320 typically before we 55 00:01:59,270 --> 00:01:58,399 halt these kind of investigations 56 00:02:01,270 --> 00:01:59,280 and 57 00:02:03,350 --> 00:02:01,280 it's a so-called model organism because 58 00:02:05,590 --> 00:02:03,360 a lot of work has been done on the plan 59 00:02:06,789 --> 00:02:05,600 its whole genome is sequenced but in any 60 00:02:08,550 --> 00:02:06,799 event 61 00:02:09,350 --> 00:02:08,560 this particular investigator is looking 62 00:02:11,750 --> 00:02:09,360 to 63 00:02:14,869 --> 00:02:11,760 understand the effects of space flight 64 00:02:17,030 --> 00:02:14,879 stress on how that plant 65 00:02:17,830 --> 00:02:17,040 expresses its genes so 66 00:02:22,550 --> 00:02:17,840 when 67 00:02:24,550 --> 00:02:22,560 like a heat stress or a water stress it 68 00:02:27,030 --> 00:02:24,560 it expresses certain genes that makes 69 00:02:28,390 --> 00:02:27,040 certain proteins in its body and then 70 00:02:30,229 --> 00:02:28,400 we can 71 00:02:31,509 --> 00:02:30,239 arrest its development which in plant 72 00:02:33,750 --> 00:02:31,519 terms means we 73 00:02:35,030 --> 00:02:33,760 we fix them and bring them back home 74 00:02:36,949 --> 00:02:35,040 and then afterwards we can do 75 00:02:39,110 --> 00:02:36,959 biochemical analysis to understand how 76 00:02:41,910 --> 00:02:39,120 those genes were turned on and off 77 00:02:44,150 --> 00:02:41,920 so six of these guys fit inside of a 78 00:02:46,070 --> 00:02:44,160 much larger canister that looks like 79 00:02:48,949 --> 00:02:46,080 this and 80 00:02:50,630 --> 00:02:48,959 this is called the brick pdfu canister 81 00:02:52,470 --> 00:02:50,640 and you can see there's six positions 82 00:02:53,670 --> 00:02:52,480 that are each identify with numbers one 83 00:02:55,350 --> 00:02:53,680 through six 84 00:02:57,030 --> 00:02:55,360 and that's because 85 00:02:59,750 --> 00:02:57,040 the crew member may be asked to 86 00:03:01,670 --> 00:02:59,760 chemically preserve individual positions 87 00:03:04,070 --> 00:03:01,680 at different points in time 88 00:03:06,550 --> 00:03:04,080 he does that by taking a another device 89 00:03:09,589 --> 00:03:06,560 that looks and acts a whole lot like a 90 00:03:11,270 --> 00:03:09,599 fancy caulking gun and so the way the 91 00:03:14,470 --> 00:03:11,280 fancy caulking gun called an actuator 92 00:03:16,309 --> 00:03:14,480 tool works is you pull back the 93 00:03:19,670 --> 00:03:16,319 the pommel on it again just like a 94 00:03:20,630 --> 00:03:19,680 caulking gun and then 95 00:03:22,070 --> 00:03:20,640 this 96 00:03:24,070 --> 00:03:22,080 mates with the top surface of the 97 00:03:26,789 --> 00:03:24,080 canister 98 00:03:30,710 --> 00:03:28,789 in the process of crew member depressing 99 00:03:32,710 --> 00:03:30,720 the actuator then you can see that this 100 00:03:34,470 --> 00:03:32,720 this piston travels down 101 00:03:36,229 --> 00:03:34,480 in doing so there's a little bit of 102 00:03:37,990 --> 00:03:36,239 engineering magic that goes on inside 103 00:03:40,070 --> 00:03:38,000 here there's a there's a steel rod that 104 00:03:41,990 --> 00:03:40,080 gets driven down through some septas 105 00:03:43,910 --> 00:03:42,000 that steel rod is what actually pushes 106 00:03:46,630 --> 00:03:43,920 that piston then inside that i already 107 00:03:48,630 --> 00:03:46,640 explained is within the individual pdfu 108 00:03:50,550 --> 00:03:48,640 and that forces the liquid on there when 109 00:03:52,309 --> 00:03:50,560 the crew member takes this off 110 00:03:54,390 --> 00:03:52,319 at all points in time 111 00:03:57,429 --> 00:03:54,400 this device maintains three levels of 112 00:03:59,429 --> 00:03:57,439 containment so containment and 113 00:04:00,789 --> 00:03:59,439 keeping the crew safe is of course 114 00:04:02,229 --> 00:04:00,799 paramount importance when we fly in 115 00:04:03,350 --> 00:04:02,239 space 116 00:04:05,190 --> 00:04:03,360 the sort of thing that you could do 117 00:04:07,429 --> 00:04:05,200 easily on the ground by simply pouring 118 00:04:09,030 --> 00:04:07,439 something from a beaker on top of a 119 00:04:10,949 --> 00:04:09,040 of biology is a little more challenging 120 00:04:12,789 --> 00:04:10,959 in space so there there is some 121 00:04:14,470 --> 00:04:12,799 sophistication even though it's 122 00:04:16,229 --> 00:04:14,480 something that we call a brick and it 123 00:04:17,670 --> 00:04:16,239 even looks like a brick you could almost 124 00:04:19,030 --> 00:04:17,680 build yourself a fort out of these if 125 00:04:21,509 --> 00:04:19,040 you wanted to 126 00:04:23,270 --> 00:04:21,519 now these experiments and several others 127 00:04:25,749 --> 00:04:23,280 that came back on space x3 are now at